What question did this study set out to answer?

To evaluate the efficacy of AI-enabled imaging and DEEP mapping in VT ablation for improved outcomes.

June 27, 2026EP EuropaceOpen Access

Non-invasive artificial intelligence pre-imaging and decrement evoked potentials mapping guided ischemic ventricular tachycardia ablation

Q: What is the clinical evidence from this study?

Study design: Case Report. Population: Ventricular tachycardia (n=4). Intervention: Non-invasive artificial intelligence and decrement evoked potentials mapping (DEEP) guided ablation. Primary outcome: Freedom from recurrent ventricular arrhythmia or appropriate ICD discharge.

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Key result

AI and DEEP-guided VT ablation shows 100% freedom from appropriate ICD discharges in a case series.

Why the study?

Does non-invasive artificial intelligence pre-imaging and decrement evoked potentials mapping guided ablation prevent recurrent ventricular arrhythmia in patients with ischemic ventricular tachycardia?

Population

4 male patients with a history of myocardial infarction, symptomatic ventricular tachycardia, and computed…

Design

Case_series

Follow-up

1-year

Authors

VRV RadaviciusVilnius University RKR KundelisVilnius University GSG StankeviciuteVilnius University

Discussion

Member takes

Implication

Suggests durable arrhythmia suppression post-procedure; extends small RCT non-inducibility data to clinical ICD events.

Key Points

To evaluate the efficacy of AI-enabled imaging and DEEP mapping in VT ablation for improved outcomes.
Analyzed anonymized data from four male patients with myocardial infarction and VT.
Utilized electroanatomic 3D mapping integrated with CT scans processed by an AI system.
Matched DEEP potentials with arrhythmia occurrences during high-density mapping.
All patients achieved non-inducibility following stimulation protocols.
At 1-year follow-up, no ICD discharges occurred in three patients; one had self-terminating VT episodes.
One patient suffered complications unrelated to arrhythmia, indicating the procedure's general safety.

Study Design

Type

Case Report (n=4)

Structured PICO

Population

4 male patients with a history of myocardial infarction and symptomatic ventricular tachycardia who underwent AI-enabled imaging-guided ablation, followed for 1 year.

Intervention

Ventricular tachycardia ablation guided by non-invasive artificial intelligence pre-imaging (CT scans processed by AI) and decrement evoked potentials (DEEP) mapping.

Outcome

Freedom from recurrent ventricular arrhythmia or appropriate ICD discharge at 1-year follow-up.composite

AI-enabled imaging combined with DEEP mapping for ischemic VT ablation is feasible and resulted in no ICD discharges at 1 year in a small 4-patient series.

Limitations

Further prospective comparative studies are needed
Small sample size
Lack of control group
Requires further prospective comparative studies

Cite This Study

Radavicius et al. (2026) conducted a case report in Ventricular tachycardia (n=4). Non-invasive artificial intelligence and decrement evoked potentials mapping (DEEP) guided ablation was evaluated on Freedom from recurrent ventricular arrhythmia or appropriate ICD discharge. Non-invasive artificial intelligence and DEEP-guided ventricular tachycardia ablation resulted in no appropriate ICD discharges among 4 patients over 1 year of follow-up.

synapsesocial.com/papers/6a3f97a5125782b61d8658bb https://doi.org/10.1093/europace/euag105.212

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