Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 27, 2026Frontiers in PediatricsOpen Access

Minimally invasive transaxillary atrial appendage resection achieves 100% recurrence-free survival in pediatric atrial tachycardia.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does minimally invasive transaxillary atrial appendage resection improve arrhythmia control in children with focal atrial tachycardia originating from the atrial appendage?

Population

6 children with focal atrial tachycardia originating from the atrial appendage confirmed by Carto3 mapping…

Design

Cohort

Follow-up

median 13 months (IQR 6.75–16.25)

Key result

Minimally invasive transaxillary atrial appendage resection achieved immediate tachycardia termination and 100% recurrence-free survival at a median 13-month follow-up in five pediatric patients.

Authors

LWL S WangWZWeitao ZhangLZLiyun Zhao

Discussion

Loading...

Member takes

Overview

Supports appendage resection for AT termination; hypothesis-generating and should not change practice without larger prospective data.

Key Points

  • This study aims to evaluate the outcome of minimally invasive surgery for focal atrial tachycardia in children using electroanatomic mapping.
  • Single-center retrospective analysis of 27 children with atrial tachycardia, performed between January 2023 and April 2026.
  • Patients treated included five with appendage resection and one with pulsed field ablation, with follow-up averaging 13 months.
  • Data on clinical characteristics and outcomes were collected and analyzed descriptively.
  • All five patients in the appendage resection group achieved immediate termination of atrial tachycardia and restored sinus rhythm with no complications noted at follow-up.
  • In the pulsed field ablation group, while immediate success was achieved, atrial tachycardia recurred at one month post-procedure.
  • Tachycardia-induced cardiomyopathy showed improvement in left ventricular ejection fraction and fractional shortening in the three patients assessed.

Study Design

Type

Cohort (n=6)

Multicenter

No

Structured PICO

Does minimally invasive transaxillary atrial appendage resection improve arrhythmia control in children with focal atrial tachycardia originating from the atrial appendage?

P
Population
6 children (mean age 10.28 years) with focal atrial tachycardia originating from the atrial appendage refractory to medical therapy, followed for a median of 13 months.
I
Intervention
Minimally invasive transaxillary atrial appendage resection guided by Carto3 mapping (n=5) or pulsed field ablation (n=1).
O
Outcome
Immediate AT termination and sinus rhythm restoration, recurrence, and procedure-related complications.

Minimally invasive transaxillary atrial appendage resection demonstrates initial feasibility and favorable short-term outcomes for pediatric atrial appendage tachycardia refractory to medical therapy.

Limitations

  • Very small sample size and single-center retrospective design
  • Mixed, non-randomized treatment allocation
  • Short and variable follow-up
  • TIC subgroup n = 3 precludes statistical inference
  • Single PFA case limits efficacy assessment
  • Very small sample size
  • Limited follow-up duration
  • Single-center experience limiting external generalizability
  • Retrospective design

Cite This Study

Wang et al. (2026) conducted a cohort in Focal atrial tachycardia originating from the atrial appendage (AAT) (n=6). Minimally invasive transaxillary atrial appendage resection was evaluated on Immediate AT termination and sinus rhythm restoration (acute success) and recurrence. Minimally invasive transaxillary atrial appendage resection achieved immediate tachycardia termination and 100% recurrence-free survival at a median 13-month follow-up in five pediatric patients.

synapsesocial.com/papers/6a3f9785125782b61d865742https://doi.org/10.3389/fped.2026.1852142
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Series case report of efficacy and safety of radiofrequency catheter ablation to treat atrial tachycardia originating from the distal portion of the atrial appendage2025
  2. 2Atrial tachycardia of left atrial appendage origin treated with pulsed field ablation using a linear-tip catheter: a case report2025
  3. 3Electrophysiological Features of Atrial Tachyarrhythmias and Rhythm Outcome in Patients Receiving Repeat Catheter Ablation After Surgical Atrial Fibrillation Ablation Plus Left Atrial Appendage Excision2025
  4. 4Long-term efficacy of catheter ablation for reentrant atrial tachycardia in dextro-transposition of the great arteries patients after atrial switch2026
  5. 5Clinical outcomes of catheter ablation for atrial arrhythmias in adult congenital heart disease patients2026