Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 27, 2026

Association of Serum 25-Hydroxyvitamin D and Vitamin D Receptor with Hyperthyroidism: A Case-Control Observational Study from South India.

View Full Paper
Ask AI
Bookmark
Share

Authors

PNPundalik Rama NaikSRS. R. RavikiranDDDivija DA

Discussion

Loading...

Member takes

Overview

Case-control study finds low vitamin D and receptor levels linked to hyperthyroidism, suggesting a potential role in thyroid dysfunction.

Key Points

  • To evaluate the relationship between serum 25(OH)D and VDR levels with hyperthyroidism and thyroid function parameters.
  • Case-control study involving 188 participants (80 hyperthyroid patients, 108 controls)
  • Serum thyroid hormones, autoantibodies, 25(OH)D, and VDR levels were measured
  • Data analyzed using parametric and non-parametric tests, with Pearson's correlation for relationships.
  • Patients with hyperthyroidism had lower 25(OH)D levels (18.6 ± 6.9 ng/mL vs 28.9 ± 8.4 ng/mL, p<0.001)
  • VDR levels were significantly lower in hyperthyroid patients (2.14 ± 0.76 vs 3.48 ± 0.91 ng/mL, p<0.001)
  • Vitamin D deficiency was observed in 62.5% of hyperthyroid cases versus 24.1% in controls.

Cite This Study

Naik et al. (2026) studied this question.

synapsesocial.com/papers/6a3f68cdaea7db3c1953fd05https://doi.org/10.7417/ct.2026.2072
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Correlation analysis of thyroid function and vitamin D levels in patients with type 2 diabetes.2025
  2. 2Evaluation of Vitamin D3 as a diagnostic marker in hypothyroidism2025
  3. 3Assessing the correlation between vitamin D deficiency and hypothyroidism2025
  4. 4Correlation between Vitamin D levels and thyroid autoantibodies in newly diagnosed Hashimoto’s thyroiditis patients2025
  5. 5Association between subclinical hypothyroidism and vitamin D deficiency: Insights from a case-control study2025