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June 20, 2026Prague Medical ReportOpen Access

Evaluating Adherence to the 2021 Surviving Sepsis Campaign Guidelines for Sepsis and Septic Shock Management in Intensive Care Units: A Prospective Observational Study

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Prospective observational study assesses guidelines adherence in sepsis management, highlighting critical improvement areas.

The aim was to evaluate adherence to the 2021 Surviving Sepsis Campaign guidelines for sepsis management in an ICU.
Conducted as a prospective observational study over six months in an ICU
Enrolled 138 patients aged 50–80 years with sepsis or septic shock
Assessed adherence using structured case report forms and electronic medical records.
High adherence to foundational measures with 100% for intravenous crystalloids and mean arterial pressure maintenance
Adherence to the recommendation against using Quick Sequential Organ Failure Assessment as a sole tool was 0%
Suboptimal adherence at 57.1% for low-molecular-weight heparin and 75% for lung-protective ventilation.

Mugada et al. (2026) studied this question.

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