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June 20, 2026Cephalalgia

Weekend headache in migraine – fact or fiction? An observational study from DMKG-app data

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Authors

RRRuth RuscheweyhTDThomas DreslerGGGudrun Goßrau

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Overview

Observational study reveals a subgroup of migraine patients prone to weekend headaches, suggesting stress relief as a trigger.

Key Points

  • Investigate the prevalence and factors associated with weekend headache among migraine patients using electronic headache diaries.
  • Two samples of individuals with migraine were analyzed.
  • Cluster analysis and logistic regression were employed to identify headache patterns and predictive factors.
  • Samples included 1793 and 5840 patients with at least 35 headache day entries from the DMKG-App.
  • Identified a weekend headache cluster in 14-15% of patients and 18% of episodic migraine individuals.
  • Weekend cluster more frequent in working patients (p < 0.001, OR = 3.57 to 3.97) and associated with lower headache frequencies (p < 0.001, OR = 0.86).
  • A small association with older age was limited to the app-only sample and was statistically significant (p < 0.001, OR = 1.01).

Cite This Study

Ruscheweyh et al. (2026) studied this question.

synapsesocial.com/papers/6a362e91db0793dc1a5363dehttps://doi.org/10.1177/03331024261444664
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