What does this research mean for the field?

Nutritional components, including micronutrients and omega-3 fatty acids, modulate male fertility through defined molecular pathways such as oxidative stress regulation and membrane fluidity, though high-quality clinical evidence for these interventions remains limited. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This review aims to explore how nutrition impacts male reproductive health at the molecular level.

June 20, 2026Journal of Health Population and NutritionOpen Access

Nutritional modulation of male fertility: a molecular-focused scoping review

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This review aims to explore how nutrition impacts male reproductive health at the molecular level.
Conducted a scoping narrative literature review using PubMed, Scopus, and Web of Science from January 2000 to March 2025.
Included human, animal, and in vitro studies focusing on nutritional exposures and molecular mechanisms affecting semen parameters.
Nutritional components like vitamins and zinc influence sperm function through oxidative stress regulation and molecular pathways.
High processed food consumption correlates with increased sperm oxidative damage and altered signaling pathways.
Limited randomized controlled trials exist, highlighting a need for better designed studies in the area.

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Implication

Scoping review explores molecular mechanisms of nutrition on male fertility, suggesting key research gaps.

Cite This Study

Ramgir et al. (2026) studied this question.

synapsesocial.com/papers/6a362d9ddb0793dc1a535cf0 https://doi.org/10.1186/s41043-026-01374-y

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Nutritional modulation of male fertility: a molecular-focused scoping review

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Discussion

Implication

Cite This Study

Nutritional modulation of male fertility: a molecular-focused scoping review

Key Points

Discussion

Implication

Cite This Study