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June 20, 2026Frontiers in Bioengineering and BiotechnologyOpen Access

Erythropoietin in tissue engineering and beyond: a multifunctional macromolecule with emerging roles in organoids, immune modulation, and cancer research

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Authors

GSGaurav SanghviSBStefano BellucciSBSuhas Ballal

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Overview

Review explores erythropoietin's diverse therapeutic roles in tissue engineering, organoid development, and cancer biology, indicating its potential impact in regenerative medicine.

Key Points

  • This review aims to investigate erythropoietin's versatile roles beyond erythropoiesis and its potential in tissue engineering and cancer.
  • Explored EPO's biological properties and therapeutic potential in tissue repair and regeneration.
  • Analyzed innovative delivery methods including scaffold immobilization and hydrogel encapsulation.
  • Discussed EPO's role in organoid development and implications in cancer biology.
  • EPO demonstrated efficacy in regenerating multiple tissues, including bone and neural tissues.
  • Highlighted challenges such as maintaining EPO's bioactivity and controlled delivery.
  • Identified the dual role of EPO in tumor growth and immune modulation as critical for future research.

Cite This Study

Sanghvi et al. (2026) studied this question.

synapsesocial.com/papers/6a362d32db0793dc1a535acchttps://doi.org/10.3389/fbioe.2026.1708887
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