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June 19, 2026Frontiers in Cardiovascular MedicineOpen Access

Multimodality imaging aids risk stratification in arrhythmic MVP through structural, functional, and tissue characterization.

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Population

Patients with arrhythmic mitral valve prolapse (aMVP)

Design

Review

Key result

Multimodality imaging provides complementary insights into the structural, functional, and myocardial tissue characterization of arrhythmic mitral valve prolapse, aiding in phenotypic risk stratification.

Authors

GTGiovanni TavernaKGKristian GalantiACAnnagrazia Cecere

Discussion

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Overview

May refine arrhythmic mitral valve prolapse risk stratification; extends insights but leaves prospective validation open.

Key Points

  • This review aims to explore how different imaging techniques can help identify risks associated with mitral valve prolapse.
  • Critically reviews multimodality imaging methods including echocardiography, CMR, CT, and PET.
  • Organizes findings within a framework linking valve morphology to myocardial injury.
  • Discusses advanced CMR techniques for assessing myocardial tissue and fibrosis.
  • Evidence suggests a subset of MVP patients may be at risk for malignant arrhythmias and sudden cardiac death.
  • Advanced CMR techniques show potential in detecting diffuse fibrosis connected to arrhythmia vulnerability.
  • The review underscores the need for standardization and validation of imaging biomarkers in clinical practice.

Structured PICO

P
Population
Patients with arrhythmic mitral valve prolapse (aMVP)
I
Intervention
Multimodality cardiovascular imaging (echocardiography, cardiac magnetic resonance, computed tomography, and positron emission tomography)

An integrated multimodality imaging approach enhances the pathophysiological understanding and risk stratification of arrhythmic mitral valve prolapse by linking valve biomechanics to myocardial tissue remodeling.

Limitations

  • Lack of standardization and prospective validation for advanced imaging biomarkers
  • Restricted availability and resource constraints for CMR in many healthcare settings
  • Most available studies conducted in relatively small and selected cohorts

Cite This Study

Taverna et al. (2026) conducted a review in Arrhythmic mitral valve prolapse. Multimodality cardiovascular imaging was evaluated. Multimodality imaging provides complementary insights into the structural, functional, and myocardial tissue characterization of arrhythmic mitral valve prolapse, aiding in phenotypic risk stratification.

synapsesocial.com/papers/6a35982fdd3be7785e70ec9ahttps://doi.org/10.3389/fcvm.2026.1854022
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