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June 14, 2026CureusOpen Access

Thymoma Type B2 Associated with Myasthenia Gravis Presenting as Progressive Respiratory Distress: A Case Report

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Authors

HIHarun IskandarHasanuddin UniversityDRDicky RahmatNTNur Ahmad TabriHasanuddin University

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Implication

Case report illustrates diagnostic challenges in thymoma with myasthenia gravis leading to respiratory distress, highlighting clinical implications.

Key Points

  • To discuss the rare association of thymoma type B2 with myasthenia gravis and its impact on respiratory function.
  • Case report of a 54-year-old woman with myasthenia gravis and respiratory distress.
  • Diagnostic imaging with contrast-enhanced computed tomography revealed a necrotic anterior mediastinal lesion.
  • Surgical excision of the thymoma was performed, followed by histopathological examination.
  • Histopathology confirmed WHO type B2 thymoma with invasion, consistent with Masaoka-Koga stage II.
  • Patient experienced early postoperative neurological improvement and showed no persistent neuromuscular transmission abnormality on electromyography.
  • Clinical symptoms of myasthenia gravis improved after surgical intervention.

Cite This Study

Iskandar et al. (2026) studied this question.

synapsesocial.com/papers/6a2e482cb1cc60ccdea8c7e3https://doi.org/10.7759/cureus.110699
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