What question did this study set out to answer?

This case aims to demonstrate the use of an emergent transcatheter aortic valve-in-valve procedure for treating severe aortic regurgitation.

June 14, 2026JACC Case ReportsOpen Access

Emergent TAV-in-TAV for Failed Bioprosthetic Valve With Severe Aortic Regurgitation Presenting as a Myocardial Infarction

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Supports emergent TAV-in-TAV for severe AR with cardiogenic shock; extends RCT evidence to bioprosthetic valve failure in octogenarians.

This case aims to demonstrate the use of an emergent transcatheter aortic valve-in-valve procedure for treating severe aortic regurgitation.
Patient presented with chest pain and dyspnea due to severe aortic regurgitation and hypotension.
Left heart catheterization confirmed coronary artery health and presence of a failing bioprosthetic valve.
An emergent transcatheter aortic valve-in-valve procedure was performed to replace the failing valve.
Procedural success resolved severe aortic regurgitation and stabilized hemodynamics.
Patient experienced improvement in symptoms immediately following the procedure.

Wells et al. (2026) studied this question.

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