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June 13, 2026Annals of Plastic Surgery

Skin Lesion Reconstruction in Graft Versus Host Disease Using Autograft From the Bone Marrow Donor Panniculectomy Tissue

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Authors

DKDaniella KingMKMaria KalogeromitrosBGBarite Gutama

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Overview

Case report shows successful skin reconstruction for refractory cGVHD in a pediatric patient, indicating donor tissue advantages.

Key Points

  • To explore donor skin allografting as a treatment for refractory cutaneous graft-versus-host disease (cGVHD).
  • Case report of a pediatric patient with cGVHD post bone marrow transplant.
  • Split-thickness skin allograft transplantation from the donor's pannus was performed.
  • Literature review on cGVHD biology and treatment mechanisms was conducted.
  • Wounds were largely resolved within 3 months following the allograft transplantation.
  • The patient displayed significant improvement despite prior unsuccessful treatments and infections.
  • Utilization of donor pannus was highlighted as a beneficial approach in this case.

Cite This Study

King et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf41ffaef96ed7f0567bfhttps://doi.org/10.1097/sap.0000000000004798
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Biopsy-Proven Solid Organ Transplant Graft-Versus-Host Disease (SOT-GVHD) Involving the Skin, Liver, and Bone Marrow in a Simultaneous Kidney-Pancreas Transplant Recipient2025
  2. 2Targeting CD162 for Life‐Threatening Cutaneous Chronic Graft‐Versus‐Host Disease: A Case Report2026
  3. 3Cutaneous Manifestations in an Infant With Hemophagocytic Lymphohistiocytosis: Case Report2025
  4. 4Atypical Wounds in Chronic Graft‐Versus‐Host Disease and Peripheral Arterial Disease Caused by Tyrosine Kinase Inhibitors2025
  5. 5Cryopreserved Total Skin Allografts From Living Donors for Complex Wound Management: A New Paradigm in Regenerative Wound Care2025