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June 13, 2026Frontiers in PharmacologyOpen Access

The tumor microenvironment: a dynamic ecosystem and therapeutic nexus in modern oncology

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Authors

MZMeiqi ZhangYLYao LuXYXingxing Yuan

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Overview

Review evaluates the tumor microenvironment's role in cancer therapy and resistance, suggesting new treatment strategies.

Key Points

  • This review aims to analyze the tumor microenvironment's role in cancer pathogenesis and therapeutic resistance.
  • Synthesis of advances in cellular and acellular aspects of the tumor microenvironment
  • Evaluation of therapeutic strategies targeting the tumor microenvironment
  • Discussion of predictive modeling tools for personalized therapy
  • Emphasizes the TME's role in shaping tumor behavior and responses to treatments
  • Highlights new therapeutic strategies such as precision nanotechnologies and next-generation immunotherapies
  • Describes the importance of multidisciplinary approaches to reprogram the TME effectively.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf300faef96ed7f055858https://doi.org/10.3389/fphar.2026.1836055
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