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June 12, 2026Journal of the American College of Cardiology

The effect of combined aerobic and resistance exercise training on vascular function in type 2 diabetes

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Authors

AMAndrew MaioranaGOG. O’DriscollCCCraig Cheetham

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Overview

Exercise training may improve vascular function in type 2 diabetes; leaves open larger trials on clinical outcomes.

Key Points

  • This study aims to determine the impact of combined aerobic and resistance exercise training on vascular function in patients with type 2 diabetes.
  • Randomized crossover design
  • 16 patients underwent eight weeks of aerobic and resistance exercise
  • Vascular functions assessed via forearm plethysmography and high-resolution ultrasound
  • Flow-mediated dilation increased from 1.7% to 5.0% (p < 0.001) after training
  • Forearm blood flow response to acetylcholine improved (p < 0.05)
  • Endothelium-dependent vasodilation enhanced in both conduit and resistance vessels

Cite This Study

Maiorana et al. (2001) studied this question.

synapsesocial.com/papers/6a2c77dc57ffbdc7a3c24e01https://doi.org/10.1016/s0735-1097(01)01439-5
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