Key result
Female sex was associated with a higher adjusted risk of in-patient mortality following STEMI compared to men (OR 2.33; 95% CI 1.11-4.86), which attenuated after adjusting for treatment factors.
Why the study?
Does female sex impact management pathways and clinical outcomes in STEMI patients compared to male sex?
Population
1,194 consecutive STEMI patients presenting between January 2022 and December 2024 to a large tertiary…
Comparison
Female sex vs Male sex
Design
Cohort
Follow-up
In-patient
Authors
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May signal need for closer STEMI surveillance in women; leaves open whether disparities reflect modifiable factors.
Observational (n=1,194)
No
Does female sex impact management pathways and clinical outcomes in STEMI patients compared to male sex?
Odds Ratio: 2.33 (95% CI 1.11–4.86)
Women presenting with STEMI experience significant delays in diagnosis and receive less guideline-directed care compared to men, leading to worse unadjusted early outcomes that are largely explained by these treatment disparities.
Hale et al. (2026) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=1,194). Female sex vs. Male sex was evaluated on in-patient mortality (OR 2.33, 95% CI 1.11-4.86). Female sex was associated with a higher adjusted risk of in-patient mortality following STEMI compared to men (OR 2.33; 95% CI 1.11-4.86), which attenuated after adjusting for treatment factors.