What is the clinical evidence from this study?

Study design: Cohort. Population: Cardiovascular disease requiring cardiac rehabilitation (n=65). Intervention: Phase II cardiac rehabilitation program vs. Baseline. Primary outcome: SF-36 mental summary measure (MSM) score (Δ +2.6 points, p=0.003).

What question did this study set out to answer?

To evaluate the effect of a phase II cardiac rehabilitation program on health-related quality of life (HRQOL).

June 12, 2026European Journal of Preventive CardiologyOpen Access

Heartfelt gains: quality of life in phase II cardiac rehabilitation

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Why the study?

Does an exercise-based phase II cardiac rehabilitation program improve health-related quality of life in patients post-cardiovascular event?

Population

65 patients enrolled in an exercise-based phase II cardiac rehabilitation program, mean age 61.3 ± 11.1…

Design

Cohort

Key result

Phase II cardiac rehabilitation was associated with a significant increase in the SF-36 mental summary measure score from 49.47 to 52.07 (p=0.003).

Authors

IAI Araujo DFD Ferreira MVM Vilela

Discussion

Member takes

Overview

MSM gains may support mental health monitoring in cohorts; hypothesis-generating and requires randomized confirmation.

Key Points

To evaluate the effect of a phase II cardiac rehabilitation program on health-related quality of life (HRQOL).
Single center prospective cohort study
Participants completed validated questionnaires at baseline and follow-up
Analysis included physical and mental summary measures (PSM, MSM) from SF-36
Mental summary scores increased from 49.47 to 52.07 (Δ +2.6 points, p = 0.003)
Significant improvements in social functioning (+6.4 points, p = 0.002) and general health (+12.5 points, p = 0.007)
No significant changes in MacNew, Perceived Stress, or Minnesota scores.

Study Design

Type

Cohort (n=65)

Multicenter

Structured PICO

Does an exercise-based phase II cardiac rehabilitation program improve health-related quality of life in patients post-cardiovascular event?

Population

65 patients (mean age 61.3 years, 23.1% female) with multiple comorbidities including ischemic cardiomyopathy enrolled in an exercise-based phase II cardiac rehabilitation program.

Exposure

Exercise-based phase II cardiac rehabilitation (CR) program

Outcome

Health-related quality of life (HRQOL) assessed by SF-36 (including Physical and Mental Summary Measures), Macnew, Perceived stress, and Minnesota questionnaires at follow-uppatient reported

Main Result

Mean Difference: 2.6

Absolute Event Rate: 52.07% vs 49.47%

p-value: p=0.003

Phase II cardiac rehabilitation is associated with significant improvements in mental well-being and specific quality of life domains, though not all HRQOL instruments capture these changes.

Cite This Study

Araujo et al. (2026) conducted a cohort in Cardiovascular disease requiring cardiac rehabilitation (n=65). Phase II cardiac rehabilitation program vs. Baseline was evaluated on SF-36 mental summary measure (MSM) score (Δ +2.6 points, p=0.003). Phase II cardiac rehabilitation was associated with a significant increase in the SF-36 mental summary measure score from 49.47 to 52.07 (p=0.003).

synapsesocial.com/papers/6a2bd11d6550ea4541ffe88b https://doi.org/10.1093/eurjpc/zwag249.358

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June 12, 2026European Journal of Preventive CardiologyOpen Access

Heartfelt gains: quality of life in phase II cardiac rehabilitation

View Full Paper

Ask AI

Bookmark

Why the study?

Does an exercise-based phase II cardiac rehabilitation program improve health-related quality of life in patients post-cardiovascular event?

Population

65 patients enrolled in an exercise-based phase II cardiac rehabilitation program, mean age 61.3 ± 11.1…

Design

Cohort

Key result

Phase II cardiac rehabilitation was associated with a significant increase in the SF-36 mental summary measure score from 49.47 to 52.07 (p=0.003).

Authors

IAI Araujo DFD Ferreira MVM Vilela

Discussion

Member takes

Overview

MSM gains may support mental health monitoring in cohorts; hypothesis-generating and requires randomized confirmation.

Key Points

To evaluate the effect of a phase II cardiac rehabilitation program on health-related quality of life (HRQOL).
Single center prospective cohort study
Participants completed validated questionnaires at baseline and follow-up
Analysis included physical and mental summary measures (PSM, MSM) from SF-36
Mental summary scores increased from 49.47 to 52.07 (Δ +2.6 points, p = 0.003)
Significant improvements in social functioning (+6.4 points, p = 0.002) and general health (+12.5 points, p = 0.007)
No significant changes in MacNew, Perceived Stress, or Minnesota scores.

Study Design

Type

Cohort (n=65)

Multicenter

Structured PICO

Does an exercise-based phase II cardiac rehabilitation program improve health-related quality of life in patients post-cardiovascular event?

Population

65 patients (mean age 61.3 years, 23.1% female) with multiple comorbidities including ischemic cardiomyopathy enrolled in an exercise-based phase II cardiac rehabilitation program.

Exposure

Exercise-based phase II cardiac rehabilitation (CR) program

Outcome

Health-related quality of life (HRQOL) assessed by SF-36 (including Physical and Mental Summary Measures), Macnew, Perceived stress, and Minnesota questionnaires at follow-uppatient reported

Main Result

Mean Difference: 2.6

Absolute Event Rate: 52.07% vs 49.47%

p-value: p=0.003

Phase II cardiac rehabilitation is associated with significant improvements in mental well-being and specific quality of life domains, though not all HRQOL instruments capture these changes.

Cite This Study

synapsesocial.com/papers/6a2bd11d6550ea4541ffe88b https://doi.org/10.1093/eurjpc/zwag249.358

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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