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June 12, 2026European Journal of Preventive CardiologyOpen Access

A secondary prevention program with nursing telephone follow-up for ACS patients achieved LDL-C targets in 54% at 4-6 weeks, with an 18.1% event rate over 1 year.

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Why the study?

Does a secondary prevention program with telephone follow-up conducted by nursing staff improve cardiovascular risk factor targets in patients discharged after ACS who are not enrolled in cardiac rehabilitation programs?

Population

88 patients discharged after acute coronary syndrome who are not enrolled in cardiac rehabilitation…

Design

Cohort

Follow-up

1 year

Key result

A secondary prevention program with nursing telephone follow-up for ACS patients achieved LDL-C targets in 54% at 4-6 weeks, with an 18.1% event rate over 1 year.

Authors

RVR S V Rocio Sanchez VacaBBB C V Calvo BernalMTM M T Miriam Martin Toro

Discussion

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Overview

Suboptimal LDL-C control persists despite therapy; challenges guideline implementation and extends need for targeted optimization strategies.

Key Points

  • To assess the impact of a secondary prevention program with nursing telephone follow-up on patients discharged after acute coronary syndrome who did not enroll in cardiac rehabilitation programs.
  • Prospective single-center observational study
  • Follow-up at 4–6 weeks and 1 year post-discharge
  • Assessment of LDL-C, non-HDL-C, and HbA1c targets, and eligibility for dual antiplatelet therapy.
  • 54% achieved LDL-C targets at 4–6 weeks, stable at 1 year (61.2 ± 30 mg/dL at 4–6 weeks, 61 ± 32 mg/dL at 1 year)
  • Non-HDL-C control improved from 58% at 4–6 weeks to 70% at 1 year (85 ± 36 mg/dL at 4–6 weeks, 79 ± 41 mg/dL at 1 year)
  • 62% achieved HbA1c control at 4–6 weeks, rising to 68% at 1 year (6.9 ± 1.5% at 4–6 weeks, 6.6 ± 1.1% at 1 year).

Study Design

Type

Observational (n=88)

Multicenter

No

Structured PICO

Does a secondary prevention program with telephone follow-up conducted by nursing staff improve cardiovascular risk factor targets in patients discharged after ACS who are not enrolled in cardiac rehabilitation programs?

P
Population
88 patients (mean age 78, 38% women) discharged after acute coronary syndrome who were not enrolled in cardiac rehabilitation programs, followed for 1 year.
E
Exposure
Secondary prevention program with telephone follow-up conducted by nursing staff.
O
Outcome
Achievement of LDL-C, non-HDL-C, and glycated hemoglobin (HbA1c) targets at 4-6 weeks and 1 year.surrogate

A nursing-led telephone follow-up program for secondary prevention in post-ACS patients not enrolled in cardiac rehabilitation achieved favorable cardiovascular risk factor control.

Limitations

  • Elderly population with multiple comorbidities, high rate of recurrent events, and substantial polypharmacy

Cite This Study

Vaca et al. (2026) conducted an observational in Acute coronary syndrome (n=88). Secondary prevention program with telephone follow-up by nursing staff was evaluated on Achievement of LDL-C targets at 4-6 weeks. A secondary prevention program with nursing telephone follow-up for ACS patients achieved LDL-C targets in 54% at 4-6 weeks, with an 18.1% event rate over 1 year.

synapsesocial.com/papers/6a2bd11d6550ea4541ffe883https://doi.org/10.1093/eurjpc/zwag249.018
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nurse-led follow-up and digital health engagement in lipid-control after acute coronary syndrome2026
  2. 2The effect of follow-up reexamination on the long-term prognosis of patients with acute coronary syndrome undergoing coronary angiography2025 · 1 citations
  3. 3Assessment of LDL-C and HbA1c screening and management in a real-world ACS cohort in the west of Ireland2026
  4. 4Secondary Prevention Adherence and Clinical Outcomes in Diabetic Patients After Acute Coronary Syndrome2025
  5. 5Long-term impact of telemedicine for lipid control after an acute coronary syndrome2025 · 1 citations