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June 12, 2026Neurology

Therapeutic Uncertainty in Statin-Induced Necrotizing Autoimmune Myopathy: A Case Highlighting Limited Recovery Despite Aggressive Treatment (P8-9.021)

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Key result

Aggressive treatment for statin-induced necrotizing autoimmune myopathy yielded limited recovery, highlighting therapeutic uncertainty and a lack of standardized guidelines.

Population

A patient with Statin-induced necrotizing autoimmune myopathy (SINAM)

Design

Case_report

Authors

MCMaría ChacónLPLinker Viñan PaucarDMDaniel Moreno-Zambrano

Discussion

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Member takes

Overview

May warrant cautious immunosuppression in SINAM; leaves open standardized protocols and prospective trials.

Key Points

  • The aim is to present a case of statin-induced necrotizing autoimmune myopathy and its treatment challenges.
  • Aggressive treatment was administered to the patient with SINAM.
  • The case illustrates the absence of standardized guidelines for managing this condition.
  • The patient showed limited recovery despite aggressive treatment for SINAM.

Structured PICO

P
Population
A patient with Statin-induced necrotizing autoimmune myopathy (SINAM)
I
Intervention
Aggressive treatment
O
Outcome
Recovery

This case report highlights the therapeutic uncertainty and limited recovery associated with statin-induced necrotizing autoimmune myopathy despite aggressive treatment.

Cite This Study

Chacón et al. (2026) studied this question. Aggressive treatment for statin-induced necrotizing autoimmune myopathy yielded limited recovery, highlighting therapeutic uncertainty and a lack of standardized guidelines.

synapsesocial.com/papers/6a2bd1056550ea4541ffe817https://doi.org/10.1212/wnl.0000000000212859
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