What does this research mean for the field?

South Asian American and Hispanic individuals have significantly higher odds of experiencing comorbid Type 2 diabetes and mental health disorders, such as depression and anxiety, compared to White individuals. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To explore the prevalence and factors associated with comorbidity of type 2 diabetes and poor mental health in South Asian Americans and other minority populations.

June 7, 2026Diabetes

2780-LB: Co-occurrence of Type 2 Diabetes and Poor Mental Health from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) and Multiethnic Study of Atherosclerosis (MESA) Studies

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Population

Adults ≥45 years of age from the MESA and MASALA cohorts, mean age 61 years, 52.3% female.

Design

Cross-sectional

Authors

NANAHEED AHMED LWLaura C. WyattNew York University ABAlain G. BertoniUniversity of North Carolina at Chapel Hill

Discussion

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Implication

South Asian and Hispanic adults have significantly higher odds of comorbid Type 2 diabetes and mental health disorders compared to White adults.

Key Points

To explore the prevalence and factors associated with comorbidity of type 2 diabetes and poor mental health in South Asian Americans and other minority populations.
Utilized baseline data from MESA and MASALA studies.
Included adults aged 45 and older from diverse racial/ethnic backgrounds.
Applied logistic regression analyses to assess associations between T2D and mental health issues.
South Asian participants had higher odds of comorbidity with T2D and depression (OR 8.3, 95% CI 5.0-13.9) compared to Whites.
Hispanic participants also showed increased odds for T2D and depression (OR 3.3, 95% CI 2.0-5.5).
Other South Asian groups exhibited significant comorbid outcomes compared to Indian participants (OR 3.4, 95% CI 1.4-8.4).

Structured PICO

Population

Adults ≥45 years of age from the MESA (White, Chinese, Black, and Hispanic) and MASALA (South Asian) cohorts, mean age 61 years, 52.3% female.

Comparator

White participants (for main analysis) and Indian participants (for South Asian subgroup analysis)

Outcome

Comorbid binary outcomes: 1) T2D and depression, 2) T2D and anxiety, and 3) T2D and chronic burden

South Asian and Hispanic adults have significantly higher odds of comorbid Type 2 diabetes and mental health disorders compared to White adults.

Cite This Study

AHMED et al. (2026) studied this question.

synapsesocial.com/papers/6a250baa7def13d035e1bb72 https://doi.org/10.2337/db26-2780-lb

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Implication

South Asian and Hispanic adults have significantly higher odds of comorbid Type 2 diabetes and mental health disorders compared to White adults.

2780-LB: Co-occurrence of Type 2 Diabetes and Poor Mental Health from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) and Multiethnic Study of Atherosclerosis (MESA) Studies

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

2780-LB: Co-occurrence of Type 2 Diabetes and Poor Mental Health from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) and Multiethnic Study of Atherosclerosis (MESA) Studies

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider