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June 7, 2026Diabetes

In those without DM, all AANHPI subpopulations had higher adjusted mean A1c than NHW at normal, overweight, and obese BMI and for ages 30-84y, with the highest A1c seen in NHPI, Filipino, and South Asian adults.

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Why the study?

Does A1c level vary among AANHPI subpopulations compared to NHW populations across different age and BMI categories?

Population

792,905 Asian American, Native Hawaiian, and Pacific Islander members and Non-Hispanic White populations in…

Design

Cohort

Authors

YDY.G. DaidaRPRishi ParikhJLJoan C. Lo

Discussion

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Overview

A1c levels are higher in AANHPI subpopulations compared to Non-Hispanic Whites independent of diabetes status, age, sex, and BMI, highlighting the need for targeted screening and interventions.

Key Points

  • This study aims to analyze A1C levels across different AANHPI subpopulations, considering the effects of age and BMI.
  • Identified 792,905 AANHPI members from Kaiser Permanente Northern California and Hawaii between 2012-2022, aged ≥30 years with no prior cardiovascular disease.
  • Calculated mean predicted A1C values stratified by diabetes status, age, sex, and BMI, adjusting for various factors.
  • Examined interactions between race/ethnicity, age, sex, and BMI.
  • NHPI adults exhibited the highest rates of obesity (58%) and dyslipidemia (51%).
  • Among those with diabetes, A1C levels were highest in NHPIs across all age and BMI groups.
  • All AANHPI subpopulations showed higher adjusted mean A1C than NHW at normal, overweight, and obese BMIs, particularly for ages 30-84.

Structured PICO

Does A1c level vary among AANHPI subpopulations compared to NHW populations across different age and BMI categories?

P
Population
792,905 Asian American, Native Hawaiian, and Pacific Islander (AANHPI) members and Non-Hispanic White (NHW) populations in Kaiser Permanente Northern California and Hawaii from 2012-2022, aged ≥30 years with no prior cardiovascular disease.
C
Comparator
Non-Hispanic White (NHW) populations
O
Outcome
Mean predicted A1c values across race/ethnicity, stratified by diabetes status, age, sex, and BMIsurrogate

A1c levels are higher in AANHPI subpopulations compared to Non-Hispanic Whites independent of diabetes status, age, sex, and BMI, highlighting the need for targeted screening and interventions.

Cite This Study

Daida et al. (2026) studied this question.

synapsesocial.com/papers/6a250b707def13d035e1b671https://doi.org/10.2337/db26-2337-p
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