What question did this study set out to answer?

This research aims to compare the efficacy and safety of oral ferrous sulfate and IV ferric carboxymaltose for treating iron deficiency anemia during pregnancy.

June 6, 2026Annals of African Medicine

Comparative Efficacy, Safety, and Quality-of-Life Outcomes of Oral Ferrous Sulfate Versus Intravenous Ferric Carboxymaltose in the Management of Iron Deficiency Anemia During Pregnancy

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This research aims to compare the efficacy and safety of oral ferrous sulfate and IV ferric carboxymaltose for treating iron deficiency anemia during pregnancy.
A comparative analysis involving 60 pregnant women with iron deficiency anemia, randomized to receive either oral ferrous sulfate or IV ferric carboxymaltose.
Measured outcomes included hemoglobin changes, serum ferritin, packed cell volume, fatigue scores, and adverse effect profiles.
IV ferric carboxymaltose lead to a mean hemoglobin rise of 3.56 g/dL compared to 2.52 g/dL in the oral group (P < 0.001).
Serum ferritin levels significantly increased to 73.13 ng/mL in the IV group versus 22.70 ng/mL in the oral group (P < 0.001).
IV iron improved fatigue scores more effectively than oral iron (P < 0.001), with fewer gastrointestinal side effects.

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Implication

Randomized trial compares efficacy and safety of oral vs IV iron treatments in pregnant women with iron deficiency anemia, indicating a preferred IV option.

Cite This Study

Chakraborty et al. (2026) studied this question.

synapsesocial.com/papers/6a23b9f271a5da9775e75ae8 https://doi.org/10.4103/aam.aam_18_26

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Implication

Randomized trial compares efficacy and safety of oral vs IV iron treatments in pregnant women with iron deficiency anemia, indicating a preferred IV option.

Comparative Efficacy, Safety, and Quality-of-Life Outcomes of Oral Ferrous Sulfate Versus Intravenous Ferric Carboxymaltose in the Management of Iron Deficiency Anemia During Pregnancy

Key Points

Discussion

Implication

Cite This Study

Comparative Efficacy, Safety, and Quality-of-Life Outcomes of Oral Ferrous Sulfate Versus Intravenous Ferric Carboxymaltose in the Management of Iron Deficiency Anemia During Pregnancy

Key Points

Discussion

Implication

Cite This Study

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