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This review aims to summarize recent advances in nonsteroidal topical therapies for pediatric dermatological conditions including atopic dermatitis, psoriasis, alopecia areata, vitiligo, and seborrheic dermatitis.

June 6, 2026Current Opinion in PediatricsOpen Access

Emerging topical nonsteroidal therapies in pediatric dermatology: atopic dermatitis, psoriasis, alopecia areata, vitiligo, and seborrheic dermatitis

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Authors

JGJordan A. GillespieOregon Health & Science University TFTracy FunkOregon Health & Science University JDJulie DhosscheOregon Health & Science University

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Review highlights emerging nonsteroidal therapies for pediatric dermatologic conditions, suggesting new treatment pathways.

Key Points

This review aims to summarize recent advances in nonsteroidal topical therapies for pediatric dermatological conditions including atopic dermatitis, psoriasis, alopecia areata, vitiligo, and seborrheic dermatitis.
Reviewed current literature on pediatric nonsteroidal topical therapies.
Evaluated recent FDA approvals and studies on efficacy and safety.
Analyzed treatments including difamilast, roflumilast, tapinarof, and ruxolitinib.
Difamilast is now FDA approved for atopic dermatitis; roflumilast's age range for treatment has expanded.
Ruxolitinib and tofacitinib show promise in treating alopecia areata.
Long-term use of roflumilast in seborrheic dermatitis demonstrates promising efficacy and safety.

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Gillespie et al. (2026) studied this question.

synapsesocial.com/papers/6a23b9ca71a5da9775e75a63 https://doi.org/10.1097/mop.0000000000001580

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Emerging topical nonsteroidal therapies in pediatric dermatology: atopic dermatitis, psoriasis, alopecia areata, vitiligo, and seborrheic dermatitis

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Cite This Study

Emerging topical nonsteroidal therapies in pediatric dermatology: atopic dermatitis, psoriasis, alopecia areata, vitiligo, and seborrheic dermatitis

Discussion

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Implication

Key Points

Cite This Study

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