Key result
In U.S. adults aged 30 to 79 years, the prevalence of existing CVD was 9.6%, and 20.2% had an elevated (≥7.5%) 10-year predicted risk of developing CVD based on the PREVENT equations.
Population
14,184 U.S. adults aged 30 to 79 years from the National Health and Nutrition Examination Survey between…
Design
Cross-sectional
Authors
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Captured external expert commentary on this paper, strongest first. Original sources are linked where available.
“The long-term perspective is important here because what we would like to do ideally is prevent cardiovascular disease and prevent development of risk factors for cardiovascular disease. So, either preventing the disease itself from manifesting or delaying it as long as possible. When you look at the US population, when you calculate their 30-year risk, we see that the vast majority of people will have high risks and that's really the time to act by controlling or managing these risk factors.”
“We felt this was a great opportunity to take these equations, which are based on commonly measured metrics in the clinic—common risk factors—and look at the US population as a whole and predict the risk of cardiovascular disease, both in 10-year and 30-year time horizons for the entire population.”
“If you look at adults under 60, two-thirds have an elevated 30-year risk.”
Supports broader CVD risk awareness in middle-aged US adults; leaves open whether PREVENT-guided interventions reduce events.
Cross-Sectional (n=14,184)
Yes
A substantial proportion of the U.S. adult population has an elevated 10-year or 30-year predicted risk of cardiovascular disease based on the PREVENT equations, highlighting a critical need for intensive preventive efforts.
Faridi et al. (2025) conducted a cross-sectional in Cardiovascular Disease (n=14,184). Cardiovascular risk factors was evaluated on Prevalence of elevated (≥7.5%) 10-year predicted risk of developing CVD. In U.S. adults aged 30 to 79 years, the prevalence of existing CVD was 9.6%, and 20.2% had an elevated (≥7.5%) 10-year predicted risk of developing CVD based on the PREVENT equations.
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