Retrospective follow-up study assesses predictors of DKA resolution in children, highlighting clinical implications.
Key Points
This study aimed to assess the time to resolution of diabetic ketoacidosis (DKA) and identify its clinical predictors in children with type 1 diabetes.
Retrospective follow-up study of 494 medical records from a specialized hospital
Kaplan-Meier analysis used to estimate time to resolution of DKA
Cox proportional hazards regression applied to identify predictors of resolution time.
Total of 487 children followed for 12,279 person-hours; 406 children recovered (83.37% resolution rate)
Median time to resolution was 22 hours (95% CI: 18.32–25.67)
Higher RBS levels and presence of infection were associated with delayed resolution, while mild DKA and duration < 24 hours promoted faster resolution.