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May 30, 2026European Journal of Preventive Cardiology

Cardiac telerehabilitation yielded similar improvements in peak VO2 compared with center-based rehabilitation (MD 1.55; 95% CI -1.60 to 4.70) and significantly greater improvements than usual care.

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Why the study?

Does phase II cardiac telerehabilitation improve cardiorespiratory fitness and functional capacity compared to center-based cardiac rehabilitation or usual care in adults with coronary heart disease?

Population

25 RCTs pooling 2,717 adults with coronary heart disease (CHD)

Comparison

Phase II cardiac telerehabilitation with… vs Center-based cardiac rehabilitation or usual care

Design

Meta-analysis

Follow-up

3 to 12 months

Key result

Cardiac telerehabilitation yielded similar improvements in peak VO2 compared with center-based rehabilitation (MD 1.55; 95% CI -1.60 to 4.70) and significantly greater improvements than usual care.

Authors

SKSevda Ece KizilkilicJRJovana RisticGBGunhild Brørs

Discussion

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Overview

CTR matches center-based CR for physical capacity; extends access options for low-participation CHD patients.

Key Points

  • To evaluate the clinical benefits of cardiac telerehabilitation on physical capacity in patients with coronary heart disease.
  • Systematic review and meta-analysis according to PRISMA guidelines.
  • Included randomized controlled trials enrolling adults with coronary heart disease in phase II telerehabilitation with exercise training.
  • Outcomes measured included cardiorespiratory fitness and functional capacity, analyzed using random-effects meta-analysis.
  • No significant difference in improvements in VO2peak versus center-based cardiac rehabilitation at 3 months (MD: 1.55, 95% CI: −1.60 to 4.70; p = 0.168).
  • Significant improvement in VO2peak compared to usual care at 3 months (MD: 3.86, 95% CI: 3.03 to 4.69; p < 0.0001).
  • Significant improvement in 6MWT compared to usual care at 3 months (MD: 37.83, 95% CI: 22.12 to 53.53; p = 0.001).

Study Design

Type

Meta-Analysis (n=2,717)

Structured PICO

Does phase II cardiac telerehabilitation improve cardiorespiratory fitness and functional capacity compared to center-based cardiac rehabilitation or usual care in adults with coronary heart disease?

P
Population
25 RCTs pooling 2,717 adults with coronary heart disease (CHD)
I
Intervention
Phase II cardiac telerehabilitation (CTR) with exercise training as a mandatory core component
C
Comparator
Center-based cardiac rehabilitation (CBCR) or usual care
O
Outcome
Cardiorespiratory fitness (peak VO2) and functional capacity (6MWT, ISWT) at short-term (3 months) and long-term (6-12 months)surrogate

Main Result

Effect estimate: MD 1.55 (95% CI -1.60 to 4.70)

p-value: p=0.168

Cardiac telerehabilitation is an effective alternative to center-based cardiac rehabilitation for improving physical capacity in patients with coronary heart disease, offering superior benefits to usual care.

Cite This Study

Kizilkilic et al. (2026) conducted a meta-analysis in Coronary heart disease (n=2,717). Cardiac telerehabilitation vs. Center-based cardiac rehabilitation or usual care was evaluated on Cardiorespiratory fitness (peak VO2) compared with center-based cardiac rehabilitation at short-term (3 months) (MD 1.55, 95% CI -1.60 to 4.70, p=0.168). Cardiac telerehabilitation yielded similar improvements in peak VO2 compared with center-based rehabilitation (MD 1.55; 95% CI -1.60 to 4.70) and significantly greater improvements than usual care.

synapsesocial.com/papers/6a1a7f410307b78509431861https://doi.org/10.1093/eurjpc/zwag287
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