Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 14, 2026Journal of Cardiothoracic SurgeryOpen Access

Left atrial appendage occlusion resulted in intraoperative residual flow in 16% of patients, whereas no residual flow was detected after left atrial appendage resection.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does left atrial appendage occlusion compared to resection affect residual flow and early safety in patients with atrial fibrillation undergoing cardiac surgery?

Population

86 patients with atrial fibrillation who underwent concomitant left atrial appendage exclusion during…

Comparison

Left atrial appendage occlusion using… vs Left atrial appendage resection with closure…

Design

Case_series

Key result

Left atrial appendage occlusion resulted in intraoperative residual flow in 16% of patients, whereas no residual flow was detected after left atrial appendage resection.

Authors

MKMasafumi KudoHTHideki TsubotaYAYuki Akaguma

Discussion

Loading...

Member takes

Overview

In patients undergoing cardiac surgery, LAA resection was associated with no intraoperative residual flow compared to a 16% rate with suture-based occlusion, though both had favorable early safety.

Key Points

  • To report on the technique profile, closure integrity, and early safety of left atrial appendage exclusion during cardiac surgery in patients with atrial fibrillation.
  • Retrospective review of 86 patients
  • Assessment of left atrial appendage closure using suture-based techniques and devices
  • Evaluation of residual flow with transesophageal echocardiography during surgery
  • Follow-up for 30-day outcomes including mortality and reoperation rates
  • 16% of patients in the occlusion group had residual flow post-procedure
  • No residual flow detected in the resection group
  • Both techniques exhibited favorable early safety with no 30-day mortality
  • Observed differences in sinus rhythm and anticoagulation at three months; influenced by maze procedures
  • Long-term survival differences noted but require cautious interpretation

Study Design

Type

Observational (n=86)

Multicenter

No

Structured PICO

Does left atrial appendage occlusion compared to resection affect residual flow and early safety in patients with atrial fibrillation undergoing cardiac surgery?

P
Population
86 patients with atrial fibrillation who underwent concomitant left atrial appendage exclusion during cardiac surgery at a single center between 2012 and 2025
I
Intervention
Left atrial appendage occlusion using suture-based techniques or a closure device (n=19)
C
Comparator
Left atrial appendage resection with closure using sutures or a stapler (n=67)
O
Outcome
Residual flow assessed using intraoperative transesophageal echocardiographysurrogate

Main Result

Absolute Event Rate: 16% vs 0%

p-value: p=0.009

In patients undergoing cardiac surgery, LAA resection was associated with no intraoperative residual flow compared to a 16% rate with suture-based occlusion, though both had favorable early safety.

Limitations

  • Retrospective single-center design
  • Baseline imbalances between groups
  • Unequal follow-up durations
  • Lack of routine postoperative TEE to assess late residual flow
  • Small sample size and limited event numbers
  • single-center
  • retrospective
  • baseline imbalances
  • unequal follow-up duration
  • lack of standardized follow-up imaging

Cite This Study

Kudo et al. (2026) conducted an observational in Atrial fibrillation (n=86). Left atrial appendage occlusion (LAAO) vs. Left atrial appendage resection (LAAR) was evaluated on Intraoperative residual flow detected by transesophageal echocardiography (p=0.009). Left atrial appendage occlusion resulted in intraoperative residual flow in 16% of patients, whereas no residual flow was detected after left atrial appendage resection.

synapsesocial.com/papers/69ddd9cae195c95cdefd732bhttps://doi.org/10.1186/s13019-026-04017-9
View Full Paper
Ask AI
Bookmark
Share