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April 10, 2026Archives of cardiovascular diseasesOpen Access

Leadless pacemakers implanted post-TAVI demonstrated low complication rates, with complete AV conduction restoration in 38% of patients and a <1% need for transvenous upgrade at 1 year.

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Why the study?

Does leadless pacemaker implantation provide safe clinical and electrical outcomes at 1 year in patients requiring pacing after transcatheter aortic valve implantation?

Population

102 patients from four French centres who underwent transcatheter aortic valve implantation for severe…

Design

Cohort

Follow-up

1 year

Key result

Leadless pacemakers implanted post-TAVI demonstrated low complication rates, with complete AV conduction restoration in 38% of patients and a <1% need for transvenous upgrade at 1 year.

Authors

NLNicolas LelloucheEMEloi MarijonVAVincent Algalarrondo

Discussion

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Overview

Leadless pacemakers can be safely and effectively used in patients requiring pacing after TAVI, with low complication rates and excellent electrical performance at 1 year.

Key Points

  • To assess 1-year clinical and electrical outcomes of leadless pacemaker implantation in patients after transcatheter aortic valve implantation.
  • Evaluated 102 patients undergoing TAVI and leadless pacemaker implantation from July 2019 to December 2022.
  • Conducted a prospective cohort study across four French centres.
  • Followed up patients for 1 year to assess complications and electrical variables.
  • Complication rate was low, with only one cardiac tamponade and one device migration reported.
  • At 1-year follow-up, 12% of patients experienced all-cause death and heart failure hospitalization.
  • Leadless pacemaker electrical variables significantly improved, with 38% showing complete atrioventricular conduction restoration.

Structured PICO

Does leadless pacemaker implantation provide safe clinical and electrical outcomes at 1 year in patients requiring pacing after transcatheter aortic valve implantation?

P
Population
102 patients (mean age 82 ± 9 years) from four French centres who underwent transcatheter aortic valve implantation (TAVI) for severe aortic stenosis and subsequently required pacemaker implantation.
I
Intervention
Leadless pacemaker implantation (Micra) following transcatheter aortic valve implantation.
O
Outcome
1-year clinical and electrical outcomes (including complications, all-cause death, heart failure hospitalization, and electrical variables).safety

Leadless pacemakers can be safely and effectively used in patients requiring pacing after TAVI, with low complication rates and excellent electrical performance at 1 year.

Cite This Study

Lellouche et al. (2026) studied this question. Leadless pacemakers implanted post-TAVI demonstrated low complication rates, with complete AV conduction restoration in 38% of patients and a <1% need for transvenous upgrade at 1 year.

synapsesocial.com/papers/69d893626c1944d70ce04687https://doi.org/10.1016/j.acvd.2026.02.004
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Leadless vs. transvenous pacemaker strategy following transcatheter aortic valve replacement: a systematic review and meta-analysis2026
  2. 2Leadless Pacemaker Implantation in High‐Risk Patients: Real‐World Outcomes From a Multicenter Israeli Registry2026 · 1 citations
  3. 3Leadless pacemaker implantation after transcatheter tricuspid valve replacement: first experiences and safety of the jugular approach2026
  4. 4Headless Pacemaker in Bradyarrhythmia After Transcatheter Aortic Valve Replacement: A Meta-Analysis2026
  5. 5Left ventricular wire pacing technique in transcatheter aortic valve replacement2025 · 1 citations