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January 9, 2026AJP Heart and Circulatory PhysiologyOpen Access

Light-to-moderate aerobic exercise increased aortic wall stress in patients with thoracic aortic disease, but all values remained below the aneurysmal rupture threshold.

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Key result

Light-to-moderate aerobic exercise increased aortic wall stress in patients with thoracic aortic disease, but all values remained below the aneurysmal rupture threshold.

Authors

RSRachel J. SkowSFStephen FoulkesRTR Thompson

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Overview

Quantifies aortic wall stress during aerobic exercise in individuals with thoracic aortic disease, highlighting its safety for physical activity.

Key Points

  • The study aims to quantify aortic wall stress and mechanical efficiency during aerobic exercise in individuals with thoracic aortic disease.
  • Fourteen participants with stable thoracic aortic disease and eleven age-matched controls were assessed.
  • Cardiac and aortic evaluations were conducted using magnetic resonance imaging (MRI).
  • Aortic wall stress and mechanical efficiency were measured at rest and during light-to-moderate intensity exercise.
  • Ascending aortic wall stress increased with light-to-moderate intensity exercise in both groups.
  • All measured wall stress values remained below the aneurysmal rupture threshold.
  • Patients with thoracic aortic disease showed lower mechanical efficiency in the ascending aorta compared to controls.

Cite This Study

Skow et al. (2025) studied this question. Light-to-moderate aerobic exercise increased aortic wall stress in patients with thoracic aortic disease, but all values remained below the aneurysmal rupture threshold.

synapsesocial.com/papers/69612fe430ef6c21f6853f4dhttps://doi.org/10.1152/ajpheart.00829.2025
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exercise Capacity and Mortality among Men Referred for Exercise Testing2002 · 4,147 citations
  2. 2Psychophysical bases of perceived exertion1982 · 16,661 citations