What is the clinical evidence from this study?

Study design: Cohort. Population: uncontrolled blood pressure (n=250). Intervention: Pharmacist-led intervention vs. Standard care. Primary outcome: Medication adherence rate (RR 1.75, 95% CI 1.30-2.34, p=<0.001).

What type of study is this?

This is a Pre-Registered Trial study.

What does this research mean for the field?

Pharmacist-led intervention significantly improves medication adherence rates and reduces blood pressure in patients with uncontrolled hypertension. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

What question did this study set out to answer?

To evaluate the impact of a pharmacist-led intervention on medication and lifestyle non-adherence among hypertensive patients.

January 9, 2026Discover Health SystemsOpen Access

Pharmacist-led intervention significantly improved medication adherence rates compared to standard care.

Q: What are the key findings of this study?

Q: What type of study is this?

This is a Pre-Registered Trial study.

Q: What does this research mean for the field?

Pharmacist-led intervention significantly improves medication adherence rates and reduces blood pressure in patients with uncontrolled hypertension. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

Q: What question did this study set out to answer?

To evaluate the impact of a pharmacist-led intervention on medication and lifestyle non-adherence among hypertensive patients.

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Key result

Pharmacist-led intervention significantly improved medication adherence rates compared to standard care.

Authors

AIAduke Elizabeth Ipingbemi RARasaq Adisa WEWilson O. Erhun

Discussion

Member takes

Overview

Quasi-randomised study demonstrates improved medication adherence and blood pressure control in hypertensive patients, suggesting pharmacists play a crucial role.

Key Points

To evaluate the impact of a pharmacist-led intervention on medication and lifestyle non-adherence among hypertensive patients.
Quasi-randomised study conducted in two tertiary healthcare facilities
200 hypertensive patients were enrolled and divided into control and intervention groups
Patients completed baseline questionnaires assessing adherence to medication, diet, and physical activity
The intervention group received educational support tailored to their specific needs over 6 months
Statistical analyses included descriptive and inferential statistics with significance set at p < 0.05.
Intervention group showed a significant reduction in systolic and diastolic blood pressure from baseline
Medication and dietary adherence improved significantly in the intervention group
Dietary adherence score increased from 49.0 to 55.5 in the intervention group (p < 0.001)
Control group showed no significant changes in dietary adherence
Physical activity scores slightly increased, but changes were not statistically significant.

Study Design

Type

Cohort (n=250)

Multicenter

PICO

Population

uncontrolled blood pressure (n=250)

Intervention / Comparator

Pharmacist-led intervention vs Standard care

Primary Outcome

Medication adherence rate — RR 1.75 (1.30-2.34), p=<0.001

Main Result

Effect estimate: RR 1.75 (95% CI 1.30-2.34)

Absolute Event Rate: 70% vs 40%

p-value: p=<0.001

Limitations

Lack of participant diversity
Short follow-up duration
Self-reported adherence may introduce bias

Cite This Study

Ipingbemi et al. (2025) conducted a cohort in uncontrolled blood pressure (n=250). Pharmacist-led intervention vs. Standard care was evaluated on Medication adherence rate (RR 1.75, 95% CI 1.30-2.34, p=<0.001). Pharmacist-led intervention significantly improved medication adherence rates compared to standard care.

synapsesocial.com/papers/69612fde30ef6c21f6853e7f https://doi.org/10.1007/s44250-025-00337-0

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January 9, 2026Discover Health SystemsOpen Access

Pharmacist-led intervention significantly improved medication adherence rates compared to standard care.

View Full Paper

Ask AI

Bookmark

Key result

Pharmacist-led intervention significantly improved medication adherence rates compared to standard care.

Authors

AIAduke Elizabeth Ipingbemi RARasaq Adisa WEWilson O. Erhun

Discussion

Member takes

Overview

Quasi-randomised study demonstrates improved medication adherence and blood pressure control in hypertensive patients, suggesting pharmacists play a crucial role.

Key Points

To evaluate the impact of a pharmacist-led intervention on medication and lifestyle non-adherence among hypertensive patients.
Quasi-randomised study conducted in two tertiary healthcare facilities
200 hypertensive patients were enrolled and divided into control and intervention groups
Patients completed baseline questionnaires assessing adherence to medication, diet, and physical activity
The intervention group received educational support tailored to their specific needs over 6 months
Statistical analyses included descriptive and inferential statistics with significance set at p < 0.05.
Intervention group showed a significant reduction in systolic and diastolic blood pressure from baseline
Medication and dietary adherence improved significantly in the intervention group
Dietary adherence score increased from 49.0 to 55.5 in the intervention group (p < 0.001)
Control group showed no significant changes in dietary adherence
Physical activity scores slightly increased, but changes were not statistically significant.

Study Design

Type

Cohort (n=250)

Multicenter

PICO

Population

uncontrolled blood pressure (n=250)

Intervention / Comparator

Pharmacist-led intervention vs Standard care

Primary Outcome

Medication adherence rate — RR 1.75 (1.30-2.34), p=<0.001

Main Result

Effect estimate: RR 1.75 (95% CI 1.30-2.34)

Absolute Event Rate: 70% vs 40%

p-value: p=<0.001

Limitations

Lack of participant diversity
Short follow-up duration
Self-reported adherence may introduce bias

Cite This Study

synapsesocial.com/papers/69612fde30ef6c21f6853e7f https://doi.org/10.1007/s44250-025-00337-0

View Full Paper

Ask AI

Bookmark