What type of study is this?

This is a Meta-Analysis study (also classified as: Systematic Review).

What does this research mean for the field?

Sleep-disordered breathing (SDB) is highly prevalent in patients with aortic stenosis (AS), with a prevalence rate of 76%. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

What question did this study set out to answer?

This review examines the relationship between sleep-disordered breathing and aortic stenosis, focusing on prevalence and clinical impact.

January 9, 2026Sleep Medicine ResearchOpen Access

Sleep Disordered-Breathing and Aortic Valve Stenosis: A Systematic Review and Meta-Analysis

Q: What is the clinical evidence from this study?

Study design: Systematic Review. Population: Aortic Stenosis. Primary outcome: Prevalence of sleep-disordered breathing in aortic stenosis patients (95% CI 63%-89%).

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Key result

The meta-analysis revealed a high prevalence of sleep-disordered breathing (76%) among patients with aortic stenosis, indicating a significant association between the two conditions.

Key Points

This review examines the relationship between sleep-disordered breathing and aortic stenosis, focusing on prevalence and clinical impact.
Conducted a systematic review following PRISMA guidelines.
Searched multiple databases for observational studies of adults with both conditions.
Extracted data on prevalence and outcomes, employing quality assessments.
Performed meta-analyses using odds ratios and prevalence estimates.
Pooled prevalence of sleep-disordered breathing in aortic stenosis patients was 76%.
Observed rates of obstructive sleep apnea at 49% and central sleep apnea at 51%.
Findings showed that males had a higher prevalence of sleep-disordered breathing (OR=1.68).
Patients with sleep-disordered breathing had higher odds of having aortic stenosis (OR=1.16).

Study Design

Type

Systematic Review

Multicenter

Yes

PICO

Population

Aortic Stenosis

Primary Outcome

Prevalence of sleep-disordered breathing in aortic stenosis patients (63%-89%)

Limitations

Results are limited by the small number of studies included
Heterogeneity across studies
Mostly conducted in Germany, which may limit generalizability
Short or intermediate-term follow-up without a clear understanding of long-term outcomes

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Systematic review finds high prevalence of sleep-disordered breathing in aortic stenosis, suggesting significant health implications.

Cite This Study

Heba Ramadan (2025) conducted a systematic review in Aortic Stenosis. The meta-analysis revealed a high prevalence of sleep-disordered breathing (76%) among patients with aortic stenosis, indicating a significant association between the two conditions.

synapsesocial.com/papers/69612fdc30ef6c21f6853df7 https://doi.org/10.17241/smr.2025.03188

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Sleep Disordered-Breathing and Aortic Valve Stenosis: A Systematic Review and Meta-Analysis

Key Points

Study Design

PICO

Limitations

Discussion

Implication

Cite This Study

Sleep Disordered-Breathing and Aortic Valve Stenosis: A Systematic Review and Meta-Analysis

Key Points

Study Design

PICO

Limitations

Discussion

Implication

Cite This Study

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