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January 9, 2026Obesity Science & PracticeOpen Access

Fit-Fat Index variants significantly improved cardiovascular death risk prediction, with HRs of 0.82 for FFI BMI and 0.78 for FFI WHR compared to traditional measures.

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Key result

Fit-Fat Index variants significantly improved cardiovascular death risk prediction, with HRs of 0.82 for FFI BMI and 0.78 for FFI WHR compared to traditional measures.

Authors

NINzechukwu Michael IsiozorUniversity of Eastern FinlandSKSetor K. KunutsorUniversity of LeicesterSKSudhir KurlUniversity of Eastern Finland

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Overview

Prospective analysis examines mortality connections with fitness and fatness indices in men, suggesting improved cardiovascular risk assessment.

Key Points

  • The study aims to investigate the connections between cardiorespiratory fitness, fatness indices, and mortality outcomes.
  • Assessed cardiorespiratory fitness and fatness indices (BMI, WHR, WHtR) in 1089 men aged 42–61 years.
  • Calculated Fit-Fat Index variants by dividing CRF by each fatness measure.
  • Utilized hazard ratios to evaluate mortality risk with multivariable adjustments.
  • Recorded 288 CVD deaths and 695 all-cause deaths over a median follow-up of 31.2 years.
  • Higher CRF correlates with reduced CVD mortality (HR 0.81 per 1 SD increase).
  • FFI variants demonstrated lower risk ratios for CVD mortality compared to fatness indices alone.

Cite This Study

Isiozor et al. (2026) studied this question. Fit-Fat Index variants significantly improved cardiovascular death risk prediction, with HRs of 0.82 for FFI BMI and 0.78 for FFI WHR compared to traditional measures.

synapsesocial.com/papers/69612fd030ef6c21f6853caahttps://doi.org/10.1002/osp4.70108
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