PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
January 9, 2026BMC GeriatricsOpen Access

The prevalence and burden of chronic kidney disease, patterns of anticoagulation prescribing, and major bleeding risk in older adults with atrial fibrillation

View Full Paper
Ask AI
Bookmark
Share

Key result

Older adults with atrial fibrillation and chronic kidney disease face a high risk of major bleeding, necessitating a holistic approach to stroke prophylaxis.

Authors

HAHawa O. AbuFCFelipe Fernandez del CastilloWWWeijia Wang

Discussion

Loading...

Member takes

Overview

Observational study highlights major bleeding risks in older adults with AF and comorbid CKD, suggesting a more integrated care approach.

Key Points

  • To examine the prevalence and impacts of chronic kidney disease in older adults with atrial fibrillation, focusing on anticoagulation risks.
  • Assessment of prescribing patterns of anticoagulants.
  • Evaluation of risks associated with major bleeding.
  • Analysis of patient characteristics including frailty and comorbid conditions.
  • Increased risk of major bleeding in patients with severely impaired kidney function.
  • Significant prevalence of frailty and polypharmacy among older adults with AF and CKD.
  • Need for holistic management approaches highlighted.

Cite This Study

Abu et al. (2025) studied this question. Older adults with atrial fibrillation and chronic kidney disease face a high risk of major bleeding, necessitating a holistic approach to stroke prophylaxis.

synapsesocial.com/papers/696128f244c2cd6c68456c80https://doi.org/10.1186/s12877-025-06888-4
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment2005 · 26,182 citations