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January 9, 2026European Journal of Applied PhysiologyOpen Access

Resistance-trained athletes exhibit significantly greater left ventricular mass and wall thickness compared to untrained individuals, without impairing systolic function.

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Key result

Resistance-trained athletes exhibit significantly greater left ventricular mass and wall thickness compared to untrained individuals, without impairing systolic function.

Authors

ASAbigail M SaundersRJR. JonesJRJoanna Richards

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Overview

Observational study compares cardiac structure and function in resistance-trained athletes and untrained individuals, indicating notable adaptations.

Key Points

  • This research aims to compare cardiac structure and systolic function between resistance-trained athletes and untrained males.
  • Conducted an observational cross-sectional study.
  • Echocardiographic examinations were performed on male athletes and matched untrained volunteers.
  • Measured resting blood pressure and gathered anthropometric data for cardiac parameter indexing.
  • Resistance-trained athletes showed greater septal and posterior wall thickness compared to untrained individuals.
  • Resistance-trained individuals had a significantly higher absolute left ventricular mass.
  • Functional parameters like stroke volume and E/A ratio differed significantly, with no impairment in left ventricular function.

Study Design

Type

Observational (n=24)

Multicenter

No

PICO

P
Population
Cardiac structure and systolic function (n=24)
I
Intervention / Comparator
Resistance training vs Untrained individuals
O
Primary Outcome
Left ventricular mass (LVM) and cardiac wall thickness comparison — null (null), p=<0.001

Main Result

Effect estimate: null (95% CI null)

Absolute Event Rate: 275.19% vs 161.63%

p-value: p=<0.001

Limitations

  • Small sample size of 24 participants
  • Single gender (male) in both groups
  • Potential self-reporting bias in training patterns

Cite This Study

Saunders et al. (2025) conducted an observational in Cardiac structure and systolic function (n=24). Resistance training vs. Untrained individuals was evaluated on Left ventricular mass (LVM) and cardiac wall thickness comparison (null, 95% CI null, p=<0.001). Resistance-trained athletes exhibit significantly greater left ventricular mass and wall thickness compared to untrained individuals, without impairing systolic function.

synapsesocial.com/papers/69609567f6dae357db7c1498https://doi.org/10.1007/s00421-025-06060-1
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