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January 8, 2026Journal of Clinical MedicineOpen Access

Among elderly patients, major bleeding occurred more frequently (7.7% vs. 4.1%) after minimally invasive aortic valve replacement, highlighting increased postoperative morbidity.

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Key result

Among elderly patients, major bleeding occurred more frequently (7.7% vs. 4.1%) after minimally invasive aortic valve replacement, highlighting increased postoperative morbidity.

Authors

LALukman AmanovARArian Arjomandi RadSASadeq Ali-Hasan-Al-Saegh

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Overview

Retrospective cohort study evaluates safety of MIAVR in elderly patients, suggesting it can reduce procedural trauma.

Key Points

  • To assess the safety and feasibility of minimally invasive aortic valve replacement (MIAVR) in elderly patients.
  • Retrospective cohort study including 990 patients
  • 261 patients aged 70 years or older in elderly cohort
  • Follow-up at least 30 days postoperative
  • Utilized multivariable logistic regression and Kaplan–Meier survival analyses
  • Elderly cohort showed higher rates of major bleeding (7.7% vs. 4.1%)
  • Increased permanent pacemaker implantation in elderly (10% vs. 5.8%)
  • Higher rates of sepsis in the elderly cohort (3.4% vs. 1.1%)
  • 30-day mortality was higher in elderly (4.6% vs. 1.6%)
  • Rates of stroke and myocardial infarction were low and comparable across age groups.

Cite This Study

Amanov et al. (2026) studied this question. Among elderly patients, major bleeding occurred more frequently (7.7% vs. 4.1%) after minimally invasive aortic valve replacement, highlighting increased postoperative morbidity.

synapsesocial.com/papers/69608779fa51ca23bb980984https://doi.org/10.3390/jcm15010354
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The efficacy and safety of transcatheter aortic valve replacement in elderly patients with aortic stenosis2025
  2. 2Transcatheter Aortic Valve Implantation in Nonagenarians: A Comparative Analysis of Baseline Characteristics and 1-Year Outcomes2025
  3. 3Clinical Outcomes after Transcatheter Aortic Valve Implantation in Nonagenarian Patients: A Retrospective Population-Based Cohort Study2025
  4. 4Minimally Invasive Mitral Valve Surgery in Patients Aged ≥75 Years: An Expanding Standard of Care2025 · 1 citations
  5. 5Twenty years’ experience with minimally invasive aortic valve repair2025