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January 6, 2026Molecular BiomedicineOpen Access

Pro-resolving lipid mediators in diseases: exploring the molecular basis and clinical implication

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Authors

CLchaofu liZWZhen WangYYYukun Yang

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Overview

This review highlights the role of pro-resolving lipid mediators in inflammation resolution and therapeutic strategies for diseases.

Key Points

  • This paper summarizes the role of pro-resolving lipid mediators in managing inflammation and their clinical implications.
  • Review of literature on pro-resolving lipid mediators and their biological functions
  • Discussion of biosynthesis, signaling pathways, and therapeutic strategies
  • Evaluation of challenges in clinical translation
  • Identification of pro-resolving lipid mediators like resolvins and lipoxins
  • Demonstration of their role in enhancing efferocytosis and tissue regeneration
  • Discussion of obstacles to clinical application, including metabolic inactivation and limited delivery strategies

Cite This Study

li et al. (2026) studied this question.

synapsesocial.com/papers/695d8e5f3483e917927a575chttps://doi.org/10.1186/s43556-025-00400-5
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