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December 20, 2025European Journal of Preventive Cardiology

Myocardial fibrosis and its relationship with ventricular arrhythmias and reduced ventricular systolic function in young and veteran endurance athletes

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Authors

JPJarne De PaepePDPaolo D’AmbrosioRBRuben De Bosscher

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Overview

Cross-sectional study shows myocardial fibrosis relates to ventricular arrhythmias in middle-aged endurance athletes, suggesting higher risk.

Key Points

  • To explore the prevalence of myocardial fibrosis and its relationship with ventricular arrhythmias and reduced ventricular systolic function in endurance athletes.
  • Evaluated 296 young and 138 middle-aged male endurance athletes alongside 66 non-athletic controls.
  • Cardiac magnetic resonance imaging assessed myocardial fibrosis and biventricular function.
  • Holter monitoring quantified ventricular arrhythmias.
  • Non-hinge-point fibrosis was more prevalent in middle-aged athletes (20%) than in young athletes (3%) and controls (9%).
  • Reduced left ventricular ejection fraction was more frequent in middle-aged athletes (23%) compared to controls (8%).
  • Middle-aged athletes showed higher rates of ventricular arrhythmias compared to young athletes.

Cite This Study

Paepe et al. (2025) studied this question.

synapsesocial.com/papers/6945e9325151ab1219e4d6b1https://doi.org/10.1093/eurjpc/zwaf715
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