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December 8, 2025BloodOpen Access

Comparative epidemiological analysis of hematological malignancies in adolescents and young adults (AYA) in the United States of America (USA), 1990–2021, with projections to 2040

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Authors

NKNiladri KalSMSudipto Mukherjee

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Overview

Comparative analysis reveals declining incidence and mortality rates for AYA leukemia and lymphomas, indicating key risk factors impact outcomes.

Key Points

  • Declining trends were observed in incidence and mortality rates for AYA leukemia and lymphomas, suggesting improved outcomes.
  • In 2021, there were 2,267 cases of leukemia in AYA along with 1,086 associated deaths in the USA.
  • Analysis using data from 1990 to 2021 highlighted key risk factors like high BMI and smoking in AYA hematological malignancies.
  • These findings underscore regional disparities and highlight the impact of lifestyle factors on AYA cancer outcomes.

Cite This Study

Kal et al. (2025) studied this question.

synapsesocial.com/papers/69362f7d4fa91c937236e45dhttps://doi.org/10.1182/blood-2025-1635
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