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December 8, 2025BloodOpen Access

Real-world outcomes in T-cell/histiocyte-rich large B-cell lymphoma: Insights from the largest u.S. cohort to date

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Authors

LRLaura Reyes-UribeJMJoel MichalekLBLeyla Bojanini

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Overview

Retrospective analysis of THRLBCL reveals similar survival outcomes despite socioeconomic differences in U.S. cohorts.

Key Points

  • Overall survival rates were similar for patients treated at ACPs and CCPs, indicating effective care delivery across settings.
  • Analysis included 1,938 THRLBCL patients, of which 894 were treated at ACPs and 632 at CCPs, showcasing demographic disparities.
  • Employing Kaplan-Meier and Cox models, the study adjusted for variables impacting overall survival and demographic profiles.
  • Findings suggest standardized treatment approaches can ensure uniform outcomes in T-cell/histiocyte-rich large B-cell lymphoma across various facilities.

Cite This Study

Reyes-Uribe et al. (2025) studied this question.

synapsesocial.com/papers/69362f764fa91c937236e407https://doi.org/10.1182/blood-2025-3662
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