Analysis shows worse overall survival in Hispanic and Black patients after hematopoietic cell transplantation, indicating disparities in donor selection.
Key Points
Overall survival varies by donor type, with matched unrelated donors showing 65% 2-year OS in adverse conditions.
Older age and certain malignancies correlate with lower OS rates, with 40% presenting with acute myeloid leukemia.
Cohort analysis conducted on over 4,000 adults receiving post-transplant cyclophosphamide for graft-versus-host disease prevention.
Findings underline the need for tailored donor selection based on race and ethnicity in hematopoietic cell transplantation.