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December 8, 2025BloodOpen Access

Temporal trends and disparities in cardiovascular Disease–Related mortality in older adults with co-morbid anemia from 1999 to 2023 in the United States: A CDC wonder database analysis

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Authors

ARAhmed RazaDHDania Hussain

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Overview

Analysis reveals declining mortality rates for anemic older adults, indicating disparities by sex and race in cardiovascular disease outcomes.

Key Points

  • CVD-related mortality among older adults with anemia declined from 34.6 in 1999 to 26.3 in 2023, showcasing a significant reduction.
  • Men showed a higher age-adjusted mortality rate compared to women, while women had a more considerable decline over time.
  • Statistical analysis utilized the CDC WONDER database to evaluate mortality trends based on sex, race, and geography.
  • Disparities were evident among risk groups, highlighting the importance of addressing anemia treatment to reduce cardiovascular mortality.

Cite This Study

Raza et al. (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e2a0https://doi.org/10.1182/blood-2025-6461
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Also Consider

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  1. 1Trends and disparities in ischemic heart disease and anemia-related mortality in adults aged ≥ 65 years in the United States from 1999 to 2023: A CDC wonder database analysis2025
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  3. 3Trends and disparities in anemia and COPD-related mortality among adults in the United States from 1999 to 2023: A CDC wonder database analysis2025
  4. 4Trends and disparities in nutritional anemia-related mortality in the elderly in theunited states from 1999 to 2023: A CDC wonder database analysis2025
  5. 5Trends and disparities in anemia and pneumonia-related mortality in the United States from 1999 to 2023: A CDC wonder database analysis2025