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December 8, 2025BloodOpen Access

Association between absolute eosinophil count and outcomes in sickle cell disease

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Retrospective cohort analysis shows no link between eosinophil count and length of stay in sickle cell disease, implying limited clinical utility.

Length of stay was not significantly associated with absolute eosinophil count in sickle cell disease patients.
Among 2902 patients studied, the mean age was 31 years, predominantly black and non-Hispanic.
Assessment used ICD-10 diagnosis codes and involved analysis of comorbidity scores.
Findings may suggest that absolute eosinophil count has limited predictive value in the clinical setting.

Fadel et al. (2025) studied this question.

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Retrospective cohort analysis shows no link between eosinophil count and length of stay in sickle cell disease, implying limited clinical utility.