December 8, 2025BloodOpen Access

Efficacy of erythropoietin and intravenous iron for treatment of critical anemia in patients who decline blood transfusions for religious reasons

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DODanielle Olonoff DLDavid Levitz

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Implication

Observational analysis reveals 74% hemoglobin recovery in patients refusing blood transfusions, suggesting EPO and IV iron can help manage critical anemia.

Key Points

Hemoglobin recovery occurred in 74% of patients treated with erythropoietin and intravenous iron.
The median increase in hemoglobin was 4.4 g/dL and the average time to recovery was 13 days.
Retrospective observational study utilized patient data from Montefiore Medical Center from 2016 to 2025.
In-hospital mortality was significant at 14%, highlighting the need for further studies on iron therapy.

Cite This Study

Olonoff et al. (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e259 https://doi.org/10.1182/blood-2025-4919

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Implication

Observational analysis reveals 74% hemoglobin recovery in patients refusing blood transfusions, suggesting EPO and IV iron can help manage critical anemia.

Efficacy of erythropoietin and intravenous iron for treatment of critical anemia in patients who decline blood transfusions for religious reasons

Discussion

Member takes

Implication

Key Points

Cite This Study

Efficacy of erythropoietin and intravenous iron for treatment of critical anemia in patients who decline blood transfusions for religious reasons

Discussion

Member takes

Implication

Key Points

Cite This Study

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