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December 8, 2025BloodOpen Access

PET/CT parameters as predictors of early progression risk in newly diagnosed multiple myeloma patients eligible for autologous stem cell transplantation

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Authors

АСА. С. СубботинBKBella KhakulovaGKGleb Kashiya

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Overview

Analysis reveals PET/CT parameters predict early progression risk in multiple myeloma, suggesting improved treatment strategies.

Key Points

  • Early progression identified in multiple myeloma patients shows significant differences in PET/CT metrics.
  • Median SUVₘₐₓ was 11.61 in early progressors, compared to 7.22 in sustained responders, with p = 0.0378.
  • Observational analysis of SUV, rSUV, and soft-tissue plasmacytomas highlights the importance of PET/CT evaluation.
  • These findings support PET/CT's role in prognosis, emphasizing the need for standardization and further studies.

Cite This Study

Субботин et al. (2025) studied this question.

synapsesocial.com/papers/69362f714fa91c937236e1d4https://doi.org/10.1182/blood-2025-7513
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