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December 8, 2025Blood

More than a bulk: Higher incidence of venous thromboembolism (VTE) in patients with primary mediastinal B-cell lymphoma compared to patients with bulky mediastinal Hodgkin lymphoma

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Authors

LMLuis Fernando de Souza MatosLTLarissa Lane Cardoso TeixeiraCFCarolina Feres

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Overview

Analysis reveals 40% incidence of VTE in primary mediastinal B-cell lymphoma, suggesting risk factors differ from bulky Hodgkin lymphoma.

Key Points

  • The incidence rate of venous thromboembolism in patients with primary mediastinal B-cell lymphoma was found to be significantly higher at 40%.
  • In the cohort of 30 patients, deep vein thrombosis made up the majority of thrombotic events, with 12 total events documented.
  • Retrospective analysis focused on oncology patients diagnosed from 2015 to 2025, revealing key insights into risk factors associated with VTE.
  • This highlights the need for targeted strategies to manage thrombotic risks in patients with primary mediastinal B-cell lymphoma.

Cite This Study

Matos et al. (2025) studied this question.

synapsesocial.com/papers/69362f714fa91c937236e170https://doi.org/10.1182/blood-2025-1361
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