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December 8, 2025BloodOpen Access

Machine learning using bayesian networks to predict response in patients with newly diagnosed Acute Myeloid Leukemia

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Authors

OCOnyee ChanNANajla Al AliSYSeongseok Yun

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Overview

Predictive model shows 74% accuracy in forecasting treatment response in newly diagnosed AML, supporting Bayesian networks for personalized therapy.

Key Points

  • The predictive model achieved a 74% area under the ROC curve in assessing treatment response.
  • Key features influencing complete response included age, cytogenetic risk, and mutations in critical genes.
  • Analysis utilized a randomized dataset of 651 AML patients receiving various frontline therapies.
  • The model enhances personalized treatment strategies, highlighting pathways affecting response to therapy.

Cite This Study

Chan et al. (2025) studied this question.

synapsesocial.com/papers/69362f6e4fa91c937236e13dhttps://doi.org/10.1182/blood-2025-4357
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