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December 8, 2025Blood

Early intervention in smoldering multiple myeloma: A systematic review of comparative prospective trials

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Authors

TNTaiga Nishihori

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Overview

Systematic review reveals early intervention improves progression-free survival in smoldering multiple myeloma, suggesting treatment efficacy may outweigh risks.

Key Points

  • Early intervention significantly improves progression-free survival in smoldering multiple myeloma.
  • A total of 182 patients from five comparative trials highlighted treatment variations impact outcomes strongly.
  • Systematic review of randomized controlled trials and prospective studies indicates potential benefits of novel treatments.
  • Balancing treatment efficacy with adverse events is critical for patient safety and effective management strategies.

Cite This Study

Taiga Nishihori (2025) studied this question.

synapsesocial.com/papers/69362f6e4fa91c937236e088https://doi.org/10.1182/blood-2025-7575
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