Systematic review identifies factors predicting response to immunosuppressive therapy in aplastic anemia, suggesting a need for personalized approaches.
Key Points
Younger age and better hematopoietic reserve improve response rates to immunosuppressive therapy.
Forty-five studies analyzed predictors of response in 6,254 patients with aplastic anemia.
Qualitative assessment highlights the significance of immunological and genetic factors.
Timely initiation of therapy is crucial for optimizing treatment outcomes in aplastic anemia.