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December 8, 2025BloodOpen Access

Pregnancy outcomes among women with sickle cell disease: A propensity score-matched analysis approach using the national inpatient sample (2017-2022)

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Authors

RMRichard Mansour

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Overview

Cohort study reports increased severe maternal morbidity and healthcare utilization in pregnancies with sickle cell disease, indicating a need for specialized care.

Key Points

  • Pregnancies complicated by sickle cell disease are linked to increased severe maternal morbidity and adverse outcomes.
  • Adjusted analysis reveals odds of preeclampsia and cesarean delivery are significantly higher in women with sickle cell disease.
  • Retrospective cohort analysis using the National Inpatient Sample shows a comprehensive assessment of maternal outcomes.
  • Findings underscore the urgency for enhanced maternal care protocols for women with sickle cell disease during pregnancy.

Cite This Study

Richard Mansour (2025) studied this question.

synapsesocial.com/papers/69362f6c4fa91c937236df9bhttps://doi.org/10.1182/blood-2025-6218
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