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December 8, 2025BloodOpen Access

The contemporary adolescent and young adult sickle cell population in Malawi

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Authors

KBKambe Banda-ZgamboUniversity of Malawi

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Implication

Follow-up analysis shows improvements in clinical outcomes for young adults with sickle cell disease, suggesting need for adult care capacity in Malawi.

Key Points

  • Overall, 94% of young adults with sickle cell disease in Malawi are alive and receiving care, emphasizing the success of hydroxyurea therapy.
  • Registered metrics include mean hemoglobin of 8.0 g/dL and 21% had received a blood transfusion during their treatment.
  • Analysis of electronic records from Kamuzu Central Hospital identified important trends in patient demographics and hospitalization rates.
  • Findings indicate critical implications for future sickle cell disease management, focusing on transitional support into adulthood.

Cite This Study

Kambe Banda-Zgambo (2025) studied this question.

synapsesocial.com/papers/69362f634fa91c937236de0dhttps://doi.org/10.1182/blood-2025-4747
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