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December 8, 2025Blood

Real-world treatment utilization, sequencing, and outcomes in Mantle Cell Lymphoma: Emerging treatment patterns in the United States

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Authors

AAAlvaro J. AlencarMXMei XueYDYuan Dong

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Overview

Real-world analysis reveals treatment sequencing, healthcare resource utilization, and outcomes in mantle cell lymphoma patients.

Key Points

  • A significant proportion of mantle cell lymphoma patients were treated with bendamustine and venetoclax in the first line, leading to important clinical outcomes.
  • Healthcare resource utilization remains high across treatment lines, with varied outpatient and inpatient service usage among different regimens.
  • Treatment patterns demonstrated an increased use of Bruton tyrosine kinase inhibitors over time, indicating a shift in therapy strategies.
  • The findings emphasize the need for novel therapeutic options, particularly in heavily pretreated population.

Cite This Study

Alencar et al. (2025) studied this question.

synapsesocial.com/papers/69362f5d4fa91c937236dc35https://doi.org/10.1182/blood-2025-8020
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