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December 8, 2025Blood

Delayed and sustained minimal residual disease response predictsfavorable outcomes in newly diagnosed multiple myeloma

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LQLugui Qiu

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Overview

Retrospective analysis shows that prolonged MRD duration predicts progression-free survival in multiple myeloma, highlighting individualized risk stratification.

Key Points

  • Delayed minimal residual disease response predicts improved outcomes in multiple myeloma patients, including better survival rates.
  • A significant association was found between prolonged MRD duration and improved progression-free and overall survival.
  • The analysis covered 1,048 newly diagnosed multiple myeloma patients over 11 years, involving longitudinal MRD monitoring.
  • Findings support the integration of MRD monitoring in therapeutic decisions and risk stratification for better patient management.

Cite This Study

Lugui Qiu (2025) studied this question.

synapsesocial.com/papers/69362f5d4fa91c937236dbffhttps://doi.org/10.1182/blood-2025-7536
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